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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
A final@>

If you have any questions or concerns about taking Cialis or interactions with other drugs, always consult your doctor or pharmacist before starting any new drug treatment regimen.

Safety and side effects of Cialis, Cialis drugs, Cialis side effects
DrugSide Effects
Cialis (Tadalafil)None
Allergic (e.g., possible chest pain)
Cialis (Tadalafil) + Alcohol

Cialis is a prescription drug and may cause side effects, even those that you may not be aware of.

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All Healthon physicians and medical providers are US-licensed and board-certified, with many having certifications in obesity medicine. Your provider will review your detailed medical intake and health history to create a customized plan based on your unique health profile, providing targeted guidance for effective and sustainable sexual health.

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PEDI pregnant women:ask doctor

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The most common side effects of Cialis and Viagra are headache, flushing, and stuffy nose. If you experience any of these side effects, talk with your doctor right away.

If you experience side effects while taking Cialis or Viagra, be sure to tell your doctor right away. Some side effects may be more common than others. Tell your doctor if you have any of these side effects that bother you or that worry you: • Feeling or being sick (nausea, stomach pain, cramps, or upset stomach) • Stomach pain • Swelling in your feet or ankles • Flushing (redness of your face, tongue, throat, or face) • A runny nose • Back pain • Lightheadedness • Muscle pain or tenderness

If you experience these side effects while taking Cialis or Viagra, tell your doctor right away. These side effects may be a sign of an underlying medical condition or a drug use problem that needs to be treated. If you experience any of the following side effects while taking Cialis or Viagra, let your doctor know right away: • Back pain or pain in your muscles • Muscle pain or tenderness • Stomach upset or cramps or diarrhea • Gas or bloating in your stools or gasping for breath • Headache or feeling a burning sensation in your eyes or skin • Flushing or stuffy nose • Tiredness or tiredness • Changes in vision, including blue tinge to your blue vision • A runny nose • Stomach discomfort or cramps or diarrhea • Trouble with swallowing • Unusual tiredness • Trouble sleeping • Trouble falling asleep or staying asleep

If you experience any side effects while taking Cialis or Viagra, let your doctor know right away. They may be able to help by adjusting the dosage or reducing your dose. Talk to your doctor about whether it’s safe to take Cialis or Viagra with food or a drink. You may also be able to help by giving your doctor a small toy program that tells you when to take the pill.

If you experience side effects while taking Cialis or Viagra, talk with your doctor right away. They may need to adjust the dosage or prescribe a different medication.

If you have any questions about taking Cialis or Viagra, talk with your doctor.

In the unlikely event that you experience an erection lasting longer than 4 hours (priapism), seek immediate medical attention. You may be at risk for permanent damage, including heart disease, nerve problems, and vision problems. You can also have an erection lasting 4 hours or longer that lasts more than 4 hours, but it won’t resolve on its own. This condition can happen only with certain medications, and your doctor will prescribe the appropriate medication for you.

Cialis and Viagra

What are Cialis and Viagra?

Cialis and Viagra are prescription-only medications that treat erectile dysfunction (ED) and its associated symptoms. Cialis and Viagra are similar in many ways. They belong to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. This class of drugs contains the active ingredient tadalafil, which works to relax the blood vessels in the penis, making it easier to get an erection during sexual stimulation. Cialis and Viagra have similar half-lives and side effects. You should not take Cialis or Viagra if you are taking nitrates (often prescribed for chest pain) or nitric oxide donors (often used for angina or chest pain).

Before you start taking any new medications, talk to your doctor about whether you should use these medications or not. They may be able to prescribe other medications or treatments that you may be taking.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

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Tadalafil is not suitable for everyone. Always consult your doctor before treatment. Factors like the type and severity of erectile dysfunction (ED) including Tadalafil may occur at a slower growth rate compared to other ED treatments such as Viagra (2.5% vs. 1.5%) and Cialis (3.9% vs. 2.1%), respectively, only with severe ED. Other treatments such as sildenafil ( retailers of tadalafil tablets sell only prescribed treatments) or diltiazem ( a lung condition that makes taking PDE5 (PDE5 inhibitor) treatment time and money harder

For a list of drugs that should be avoided while taking Tadalafil, please include the following :

•ancers who have an allergy to Tadalafil;- Patients at increased risk of priapism (a prolonged and painful erection) should have affairs with and have men crystallized with both PDE5 inhibitors- Penis stproduction;- Women who have or have had a rare condition, such as retinitis pigmentosa, usingpng (a pigment that makes them look darker in their skin;)

•any patient with a good response to treatment should take tadalafil treatment as directed.

Please tell your doctor about any other medications that you are taking, or have thought to speak to your doctor about, such as :

•HIV protease inhibitors such as tipranavir, nelfinavir,- Omeprazole

•antifungal medications such as ketoconazole and itraconazole

•mephamadine

•tamoxifen

•tamsulosin

•vincShipping and handling doesn’t change the composition of the medication. If the medication is in a film, or if it’s been treated with a cream, or if it’s been swallowed, then the composition will still be present in the medication.

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